Bartlomiej (Bartek) Waclaw
Dioscuri Centre Leader
I obtained a PhD in theoretical physics from Jagellonian University in Krakow in 2007 (supervisor: Zdzislaw Burda). After 2 years in Leipzig as a post-doc in Wolfhard Janke’s group, I moved to Edinburgh, first as a postdoc working with Martin Evans, then an independent Leverhulme Trust Early Career Research Fellow. In 2013 I was awarded a Scottish Government Personal Research Fellowship co-funded by Marie Curie Actions. Around the same time I was made a proleptic lecturer in the School of Physics and Astronomy, The University of Edinburgh. I was promoted to Reader in 2019.
My early research was in random matrix theory, complex networks, and driven diffusive systems (zero-range process, TASEP, and related models). I then moved to biological physics and worked on various theoretical and experimental projects in microbial evolution and cancer. In particular, I have published on how bacteria evolve resistance to antibiotics, how growth and migration affect genetic heterogeneity of tumours, and the growth of bacterial colonies.
See here for a short bio.
I moved to Warsaw from King’s College London University where I worked as an Administration and Finance Manager for the electron microscopy unit.
In the Dioscuri Centre I support director in running the centre and manage non-scientific aspects of the Dioscuri and NAWA grants. My responsibilities among others include managing project documentation, finances and purchasing.
Please feel free to contact me first with all the non-scientific matters.
I have a Master’s degree in Biological Chemistry (2017). Notwithstanding the foregoing, I was a postgraduate student of Project Management at SGH Warsaw School of Economics (2020) and my postgraduate thesis focused on design, project & lab managing for a specialistic chemical laboratory.
In addition, I have experience in work as a Lab Manager in prof. Robert Hołyst Team – Soft Condensed Matter Group IPC PAS. My management experience is also a monthly internship (2020) in the Scope Fluidics Group (President of the Board prof. Piotr Garstecki). There, I was focusing on learning about work management using the 5S methodology (workplace organization method).
As a specialist in the Dioscuri Centre, I will be responsible for lab management in the bacterial and cell laboratories – especially: purchasing lab supplies & chemicals, organize lab working (assistance in the preparation of certifications, keeping the laboratory clean and tidy, etc.), and support Dioscuri Team in experimental work.
I am a physicist mainly trained on Active Matter using mainly simulations of microscopic models
During my PhD (2013-2017) in the group of Hugues Chaté in CEA Saclay I studied a generic active matter model for paticles with nematic symmetry at the microscopic level. In parallel I worked on developing a biological model of Neisseria Meningitidis aggregation in collaboration with the group of Guillaume Duménil at Institut Pasteur.
I then worked for my first postdoc at the University of Bristol under the supervision of Silke Henkes (2018-2020) where I addressed myosin role during convergence-extension of epithelial tissue in the early development of the Chick embryo using an Active Vertex model.
I completed my PhD in Chemical Technology in 2017 at Professor Janina Milewska-Duda’s team at AGH University of Science and Technology in Cracow, Poland. Key area of my research was focused on capturing and kinematically describing adsorbate’s particle movement near an adsorbent’s solid wall, to investigate correlation between geometrical, structural, and energetic heterogeneity effects and their impact on adsorption mechanisms.
My early research was in synthesis and characterization of C60 fullerene hybrids with sugar addends via 1,3-dipolar cycloaddition reactions (POIG.01.01.02-14-102/09). Later, I moved on to complementary study on one-step mechanism of [2+3] cycloaddition reactions between (Z)-C-(3,4,5-trimethoxyphenyl)-N-methylnitrone and selected (E)-2-substituted nitroethenes, where for the first time I incorporated quantum-chemical calculations (DFT) to investigate four competing regio- and stereoisomeric pathways.
After completing my PhD, I have acquired extensive experience in start-up and industrial environments, working in research and development departments and being involved in transfer of technology.
Postdoc (microbiology & molecular biology)
Postdoc (cell culture)
I am a specialist in droplet-based microfluidics with a tilt towards biology. I graduated from Warsaw University of Life Sciences Biotechnology program in 2014, then I moved to the Institute of Physical Chemistry of the Polish Academy of Sciences to develop microfluidic devices for analytical chemistry and microbiology as a PhD student with professor Piotr Garstecki. I defended my doctoral thesis in 2019, and continued my projects with Piotr until 2021, when I joined the Dioscuri Centre.
Apart from studying droplets and their formation process, I have employed droplets to research experiments from different fields. I have developed e.g. a system that allows for assessing antibiotic resistance of individual bacterial cells at a high throughput, a system for preparing serial dilutions of samples in nanoliter-sized droplets, or a system for studying motion of active particles at the interface of water and oil. I used to work short-term at several institutions, such as Broad Institute of MIT and Harvard, University of Cambridge, or Dresden University of Technology.
I am an avid homecook, a beer brewer, and an aficionado of Japanese visual arts, such as manga or ukio-e.
I am trained as a geneticist. I received my doctorate (summa cum laude) in biochemistry after three years of study under the supervision of prof. Tomasz Śliwiński. The topic of my thesis was DNA base excision repair in Alzheimer’s disease. After graduation, I started working at the Institute of Fundamental Technological Research of PAS in the Department of Biosystems and Soft Matter, where I dealt with the use of microfluidic systems for the cultivation and research of microorganisms.
Apart from biology, my other passion is computer science and electronics. In particular, I am interested in the implementation of deep machine learning algorithms in the broadly understood drug design and modeling of polypeptide structures. In addition, I design and build electronic automation systems based on microcontrollers and FPGA system circuits.
I have a master’s degree in Applications of Physics in Biology and Medicine, major in Molecular Design and Bioinformatics (2019). As this lengthy title suggests, throughout my studies I had a taste of how the interplay chemistry, physics, molecular biology and programming is employed to aid scientific research.
My responsibilities at Dioscuri Centre are focused on computer modelling of intracellular bacterial colonies. Thus, I am now putting to good use the experience I have managed to gain during two summer internships – at Max Planck Institute for Developmental Biology in Birte Höcker’s group (2015), and at Laboratoire Interdisciplinaire de Physique under the supervision of Karin John (2017) – where and when I was tasked with employing programming to assist biology-related research.
Side note: I also have BSc in Physics (2020) and a special fondness for quantum biology and noise-related phenomena in both molecular biology and mesoscopic physics.
I am a biotechnologist. I obtained a Bachelor degree and a Master degree at Warsaw University. Working in microbiology lab is what I love. I have experience in bacterial genetics, bioremediation and diagnostics of bacterial gastrointestinal infections. In March-August 2020 I was involved in diagnostics of SARS-CoV-2.
As a PhD Student in Dioscuri Centre, I will be investigating bacterial response to antibiotics in laboratory models of infections.